Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi awarded medicine Nobel

The Nobel Prize in Physiology or Medicine 2025 has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for groundbreaking discoveries that explain how the body’s immune system is kept in check to prevent it from attacking its own organs.

Mary E. Brunkow (born 1961) earned her Ph.D. from Princeton University, USA, and currently serves as Senior Program Manager at the Institute for Systems Biology in Seattle. Fred Ramsdell (born 1960) received his Ph.D. in 1987 from the University of California, Los Angeles, and is now Scientific Advisor at Sonoma Biotherapeutics, San Francisco.

Shimon Sakaguchi (born 1951) obtained his M.D. in 1976 and Ph.D. in 1983 from Kyoto University, Japan, and is Distinguished Professor at the Immunology Frontier Research Center, Osaka University.